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Briefly, mice exhibiting the FUSALS phenotype (characterized by FUS translocation from the nucleus to the cytoplasm) demonstrated longer lifespan, reduced disease severity and improved histological patterns when intracellular HSPA1A was overexpressed (Piavchenko et al., 2024

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Cell therapies for autism spectrum disorder: a systematic review of clinical applications

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Data obtained from separate cultures

however, for subjects on treatment for the entire 12 months, there was a small increase in the MHFMS score compared to baseline (Table 3, p = 0.185)